Family focused therapy is more effective than crisis management for preventing relapse after a bipolar episode
Bibliographic record
Abstract
Miklowitz DJ, George EL, Richards JA, et al . A randomized study of family focused psychoeducation and pharmacotherapy in the outpatient management of bipolar disorder. Arch Gen Psych 2003;60:904–12.[OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Q For outpatients with a recent bipolar episode, does family focused therapy reduce relapse and improve adherence to drug treatment compared with a less intensive crisis management intervention? ### ![Graphic][5] Design: Randomised controlled trial. ### ![Graphic][6] Allocation: Concealed. ### ![Graphic][7] Blinding: Participants and practitioners not blinded. Blinded observers assessed results for treatment adherence. ### ![Graphic][8] Follow up period: Up to 24 months. ### ![Graphic][9] Setting: Outpatient clinic, Colorado, USA. ### ![Graphic][10] Patients: 101 people (18–62 years; mean age 36 years; 64 women) with bipolar disorder episode (DSM IIIR and DSM IV, diagnosed by Structured Clinical Interview) within past 3 months; with family support. Exclusions: neurological or developmental … [1]: {openurl}?query=rft.jtitle%253DArchives%2Bof%2BGeneral%2BPsychiatry%26rft.stitle%253DArch%2BGen%2BPsychiatry%26rft.aulast%253DMiklowitz%26rft.auinit1%253DD.%2BJ.%26rft.volume%253D60%26rft.issue%253D9%26rft.spage%253D904%26rft.epage%253D912%26rft.atitle%253DA%2BRandomized%2BStudy%2Bof%2BFamily-Focused%2BPsychoeducation%2Band%2BPharmacotherapy%2Bin%2Bthe%2BOutpatient%2BManagement%2Bof%2BBipolar%2BDisorder%26rft_id%253Dinfo%253Adoi%252F10.1001%252Farchpsyc.60.9.904%26rft_id%253Dinfo%253Apmid%252F12963672%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/archpsyc.60.9.904&link_type=DOI [3]: /lookup/external-ref?access_num=12963672&link_type=MED&atom=%2Febmental%2F7%2F2%2F49.atom [4]: /lookup/external-ref?access_num=000185155800007&link_type=ISI [5]: /embed/inline-graphic-1.gif [6]: /embed/inline-graphic-2.gif [7]: /embed/inline-graphic-3.gif [8]: /embed/inline-graphic-4.gif [9]: /embed/inline-graphic-5.gif [10]: /embed/inline-graphic-6.gif
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.007 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.022 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".