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Record W2090145950 · doi:10.1159/000240565

Combined Positive and Negative Pressure Ventilation in the Management of Severe Respiratory Distress Syndrome in Newborn Infants

2009· article· en· W2090145950 on OpenAlexaff
D.W. Roloff, E.W. Outerbridge, L Stern

Bibliographic record

VenueBiology of the Neonate · 2009
Typearticle
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsMontreal Children's Hospital
Fundersnot available
KeywordsMedicineRespiratory distressOxygenationAnesthesiaVentilation (architecture)Mechanical ventilationPositive pressureIntermittent positive pressure ventilationRespiratory failureArtificial ventilationArterial oxygen tensionTranspulmonary pressureRespiratory systemRespiratory diseaseInternal medicineLungLung volumes

Abstract

fetched live from OpenAlex

Eleven newborn infants with severe respiratory distress syndrome (RDS) were artificially ventilated with an intermittent positive pressure respirator while a continuous negative pressure of ––4 to ––8 cm H<sub>2</sub>O was maintained about the chest; thereby achieving the equivalent positive of pressure ventilation. Although only two infants ultimately survived, arterial oxygen tension was improved in all patients, with a mean rise of 69.8 ± 17.3 mm Hg. Simultaneously, the alveolar-arterial oxygen difference fell·by a mean of 63.7 ± 18.4 mm Hg, even though the infants had not improved on preceding trials of both intermittent negative and intermittent positive pressure ventilation alone. These changes are significant at a level of p < 0.01. The maintenance of a continuous transpulmonary pressure gradient is an effective method for improving arterial oxygenation in infants requiring mechanical ventilation for the respiratory failure of RDS.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.612
Threshold uncertainty score0.237

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.332
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2009
Admission routes1
Has abstractyes

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