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Record W2090673341 · doi:10.1002/cjce.20485

Theoritical analysis and simulation of five‐zone simulating moving bed for ternary mixture separation

2011· article· en· W2090673341 on OpenAlexvenueno aff
H.R. Khan, Mohammad Younas

Bibliographic record

VenueThe Canadian Journal of Chemical Engineering · 2011
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein purification and stability
Canadian institutionsnot available
FundersKorea University
KeywordsSimulated moving bedTernary operationVolumetric flow rateChromatographyChemistryMass transferSeparation (statistics)Flow (mathematics)Dispersion (optics)MechanicsAnalytical Chemistry (journal)AdsorptionMathematicsStatisticsPhysicsComputer scienceOrganic chemistry

Abstract

fetched live from OpenAlex

Abstract In the present work a mathematical model has been presented to study the behaviour of five‐zone simulating moving bed (SMB) system for the separation of a ternary mixture of certain amino acids. These are methionine, phenylalanine and tryptophan, possessing linear isotherms values. Safety margin method has been used to design the SMB system while triangle theory became the basis to calculate the operating conditions at fixed feed flow rate. It was found that for same safety factor (β) value in each zone, increase in β value causes the purity values of all product streams to increase up to a definite value. Further increase in β value shows the effect of decrease in separation efficiency, because of dominance of axial dispersion and mass transfer resistances. The effect of zone safety factor (zone flow rate βII, βIII and βIV) values on the separation performance of five‐zone SMB have also been investigated which remained an important issue in SMB current research. Increase in βII value results in rising tryptophan purity, phenylalanine purity improves due to increase in βIII value and increase in βIV value becomes the basis for enhancing methionine purity. In column profile study, the solute concentration profile diminishes due to increase in particular separation zone safety factor value. This happened due to low column switching time with high desorbent flow rate to the system. The developed mode was run in Aspen Chromatography vis 12.1. (2004) simulator for simulation studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.017
Threshold uncertainty score0.034

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.238
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2011
Admission routes1
Has abstractyes

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