2,3-Anthraceno[2.2.2]cryptand. Mutual interactions between the receptor and the signal transducing subunit
Bibliographic record
Abstract
As a complement to the study of 9,10- and 1,4-anthracenocryptands, 2,3-anthraceno[2.2.2]cryptand (1) was synthesized in order to examine the mutual influence of the two components: the cation-binding subunit and the pendent aromatic moiety. It was shown that the receptor subunit induces small perturbations to the absorption spectrum and the fine structure fluorescence spectrum of 1 that are typical of those of 2,3-disubstituted anthracene reference molecules. Conversely, the stability constants towards metal cations (Ks), determined from the electronic spectra using the LETAGROP programme, were found to be altered by the incorporated aromatic component, namely lowered by several orders of magnitude compared with those of [2.2.2]cryptand. For instance, logKs values in CH3CN for 1 were found to be: K+(8); Tl+(10); for [2.2.2]cryptand: K+(11); Tl+(12). The observed decrease of binding ability can be attributed to a relative lack of flexibility of the receptor and some hindrance to cation solvation due to the aromatic component.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".