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Record W2092020400 · doi:10.1118/1.3244130

Poster — Wed Eve—26: Dose‐Volume Histogram Analyses on the Prostate IMRT Plan for Interfraction Organ Motion Using the Gaussian Error Function

2009· article· en· W2092020400 on OpenAlexaff
James C. L. Chow, Ran Jiang, Daniel Markel

Bibliographic record

VenueMedical Physics · 2009
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsPrincess Margaret Cancer Centre
Fundersnot available
KeywordsIsocenterProstateMedicineNuclear medicineRadiation treatment planningRadiation therapyRadiologyCancer

Abstract

fetched live from OpenAlex

The Gaussian error function (GEF) model was used to carry out cumulative dose‐volume histogram (cDVH) analysis on prostate IMRT plans with interfraction organ motion. cDVHs for CTVs, shifted in the anterior‐posterior directions based on 7‐beam IMRT plans for three patients (small, medium and large prostate), were calculated and modeled using the Pinnacle3 planning system and GEF. To simulate the interfraction prostate motion, the CTV was shifted 1 cm in the anterior‐posterior directions in 2 mm steps, using the dose distribution for the plan without prostate motion. As parameters in the GEF model, namely, a, b and c, were related to the shape of the cDVH curve, evaluation of cDVHs corresponding to the prostate motion becomes possible. cDVH analysis for the CTV shifting in the anterior‐posterior directions using the GEF model showed that parameters , which were related to the maximum relative volume of the cDVH, changed symmetrically when the prostate was shifted in the anterior‐posterior directions. This change was more significant for larger prostate. For parameters b related to the slope of the cDVH, changed symmetrically from the isocenter, when the CTV was within the PTV. This was different from parameters c ( related to the maximum dose of the cDVH), which did not vary significantly with the prostate motion in the anterior‐posterior directions and prostate volume. Using the patient data, this analysis validates the GEF model, and further verified the clinical application of this mathematical model on treatment plan evaluation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.078

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0230.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.345
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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