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Low-dose hydrocortisone did not improve survival in patients with septic shock but reversed shock earlier

2008· article· en· W2092179028 on OpenAlexaffabout
François Lamontagne

Bibliographic record

VenueAnnals of Internal Medicine · 2008
Typearticle
Languageen
FieldMedicine
TopicAdrenal Hormones and Disorders
Canadian institutionsHamilton Health Sciences
Fundersnot available
KeywordsMedicineSeptic shockSepsisClinical microbiologyShock (circulatory)Internal medicineFamily medicine

Abstract

fetched live from OpenAlex

ACP Journal Club17 June 2008Low-dose hydrocortisone did not improve survival in patients with septic shock but reversed shock earlierFrancois Lamontagne, MD, MSc, Maureen O. Meade, MD, MScFrancois Lamontagne, MD, MScHamilton Health Sciences, Hamilton, Ontario, Canada (F.L., M.O.M.)Search for more papers by this author, Maureen O. Meade, MD, MScHamilton Health Sciences, Hamilton, Ontario, Canada (F.L., M.O.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-148-12-200806170-02006 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationSprung CL, Annane D, Keh D, et al. Hydrocortisone therapy for patients with septic shock. N Engl J Med. 2008;358:111-24. https://pubmed.ncbi.nlm.nih.gov/18184957Clinical Impact RatingsEmergency Med: Hospitalists: Infectious Disease: Critical Care: Reference1 Annane D, Bellissant E, Bollaert PE, et al. Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. BMJ. 2004;329:480. [PMID: 15289273] Google Scholar Author, Article, and Disclosure InformationAffiliations: Hamilton Health Sciences, Hamilton, Ontario, Canada (F.L., M.O.M.)This article was published at Annals.org on 3 June 2008. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMedical Students Can Help Avoid the Expert Bias in Medicine 17 June 2008Volume 148, Issue 12Page: JC4-6KeywordsAdrenocorticotropic hormoneCritical careIntensive care unitsPharmacistsPopulation statisticsSepsisSuperinfections ePublished: 17 June 2008 Issue Published: 17 June 2008 Copyright & PermissionsCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.866

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.280
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2008
Admission routes2
Has abstractyes

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