Bibliographic record
Abstract
To the Editor The article “Pediatric Perioperative Life Support”1 effectively covered cardiac arrest in the operating room; however, the section on Venous Air Embolism (VAE) requires an update. Management suggested that “…Immediate treatment includes lowering the operative site to below heart level if possible and flooding the operative field to prevent further air entry. Positioning the patient to prevent entry of air into the pulmonary artery helps prevent obstruction of flow to the left heart (left side down and Trendelenburg)…” This recommendation refers to the work of Durant et al.2 The pathophysiology and management of VAE have been refuted by more recent studies. Mehlhorn et al.3 anesthestized 22 dogs and monitored cardiac output along with arterial, central, and pulmonary artery pressures. Each dog received a 2.5 mL/kg IV air embolus and then positioned left lateral, right lateral, or supine. Position changes after air embolism resulted in minimal hemodynamic changes despite expected air relocation in the cardiac chambers. Recovery of pressures and cardiac output was similar for all groups. Geissler et al.4 repeated the study and included transesophageal echocardiography. Transesophageal echocardiography examination after air embolism revealed relocation of the air in the heart with position changes. However, this repositioning did not result in improved hemodynamic performance. Hemodynamc improvement occurred with increased coronary perfusion pressure. In other words, the deterioration in cardiac function was due to right ventricle ischemia (coupled with right ventricle chamber dilation with air) as opposed to an airlock in the right ventricular outflow tract. It is interesting that in both studies only the supine position did not involve the death of at least 1 animal. This point is of more than academic interest. At best, left lateral positioning of a hemodynamically unstable patient with VAE would be of no benefit. However, the lateral position would interrupt or delay cardiac massage and vasopressor therapy that are evidence-based interventions. Gary Simon, MD, FRCPC Anesthesia & Perioperative Medicine London Health Sciences Centre London Ontario, Canada [email protected]
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.009 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.008 | 0.012 |
| Insufficient payload (model declined to judge) | 0.004 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".