Continuous Potential Display of Ictal Electrocorticography
Why this work is in the frame
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Bibliographic record
Abstract
The objective of this study was to determine whether the animation of electrical activity recorded on ictal electrocorticograms (ECoGs) can demonstrate the propagation of seizure discharges from the epileptogenic zone (EZ) to the surrounding cortical area. A computer program, continuous potential display (CPD), was designed to animate the color-coded potential changes in 5-msec intervals at each recorded site. This program was used to analyze 35 ictal ECoGs recorded by subdural grid electrodes from 11 subjects who underwent epilepsy surgery for intractable partial seizures. Continuous potential display demonstrated recurrent cycles of seizure propagation from the EZ to the surrounding cortical area even when seizure discharges appeared widespread on ECoG. Hence, the EZ could be mapped at any time during the seizure course. The EZ mapped by analyzing a small fraction of ECoG during widespread seizure discharges using CPD only overlapped 69 +/- 24% (mean +/- standard deviation) of the surgical area. The EZ mapped by CPD had 34 +/- 22% false positives and 35 +/- 27% false negatives. Animation of potential changes recorded by ictal ECoG can assist in studying the temporal and spatial patterns of seizure propagation and in mapping the EZ for surgical resection.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it