A case of immunotherapy-responsive eastern equine encephalitis with diffusion-weighted imaging
Bibliographic record
Abstract
Eastern equine encephalitis (EEE) is the most severe of the mosquito-borne encephalitides, associated with 30% mortality. Age over 40, rapid progression to coma, severe hyponatremia, and CSF white blood cell count >500 at symptom onset have all been correlated with poor outcome.1,2⇓ We report a patient with poor prognostic signs in whom apparent diffusion coefficient (ADC) images revealed vasogenic edema without ischemia. He made a complete recovery after treatment with steroids and IV immunoglobulin (IVIg). A 69-year-old man from southeastern Massachusetts developed a frontal headache, fever, and mild right upper extremity weakness precipitating admission to a local hospital. The following day, he developed fever to 104 °F, rapidly progressive flaccid paraparesis, and acute respiratory failure. A CT brain scan without contrast was normal. A lumbar puncture revealed 1196 white blood cells (WBC) (80% neutrophils, 2% lymphocytes), 12 red blood cells/cubic millimeter, total protein 140 mg/dL, and glucose 74 mg/dL (serum glucose of 121 mg/dL) without organisms on Gram stain or detection of cryptococcal antigen. Serum chemistries were normal except …
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".