MétaCan
Menu
Back to cohort

Late-Appearing Abscesses after Injections of Nonabsorbable Hydrogel Polymer for HIV-Associated Facial Lipoatrophy

2007· article· en· W2095255183 on OpenAlex
Derek Jones, Alastair Carruthers, Rebecca C. Fitzgerald, G. Peter Sarantopoulos, Scott W. Binder

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueDermatologic Surgery · 2007
Typearticle
Languageen
FieldMedicine
TopicFacial Rejuvenation and Surgery Techniques
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineLipoatrophySurgeryHuman immunodeficiency virus (HIV)Cosmetic TechniquesAbscessAntiretroviral therapyViral load

Abstract

fetched live from OpenAlex

The authors have indicated no significant interest with commercial supporters. Avariety of injectable fillers have been employedto correct the stigmatizing facial lipoatrophy associated with HIV infection.1,2 A novel filler is Bio-Alcamid (Bio-Alcamid, Polymekon, Milan, Italy), which has been described as an injectable ‘‘endopros-thesis.’’3 This nonbiodegradable filler is composed of 96 % water and 4 % synthetic polymer polyalkylamide and is purported to be biologically inert.3,4 Bio-Alcamid is intended for large-volume augmentation as may be necessary in hemifacial lipoatrophy (Romberg’s disease) or HIV-associated lipoatrophy.3 Bio-Alcamid is intended for injection into the subcutaneous space in a bolus form. Fibroplasia ensues around the periphery of the balloon-like im-plant creating an injectable ‘‘prosthesis.’ ’ Recent re-ports have documented the success of Bio-Alcamid for the treatment of HIV facial lipoatrophy.5,6 We report a series of five patients who have received Bio-Alcamid for HIV associated lipoatrophy and who have developed late-appearing streptococcal bacterial abscesses. In all cases the abscesses resolved with incision and drainage and antibiotic therapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.726
Threshold uncertainty score0.684

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.275
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it