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Multiple sequence alignment with the Clustal series of programs

2003· article· en· 4,899 citations· W2095724872 on OpenAlex· 10.1093/nar/gkg500

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Abstract

The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the programs depends on a number of factors, including not only the accuracy of the results, but also the robustness, portability and user-friendliness of the programs. New features include NEXUS and FASTA format output, printing range numbers and faster tree calculation. Although, Clustal was originally developed to run on a local computer, numerous Web servers have been set up, notably at the EBI (European Bioinformatics Institute) (http://www.ebi.ac.uk/clustalw/).

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The record

Venue
Nucleic Acids Research
Topic
Genomics and Phylogenetic Studies
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
Institute of GeneticsCentre National de la Recherche Scientifique
Keywords
BiologyMultiple sequence alignmentSoftware portabilityPhylogenetic treeSequence alignmentWeb serverIndelRobustness (evolution)BioinformaticsSet (abstract data type)Computational biologyComputer scienceThe InternetGeneticsWorld Wide WebPeptide sequenceProgramming language
Has abstract in OpenAlex
yes