MétaCan
Menu
Back to cohort
Record W2097897456 · doi:10.1373/clinchem.2013.220467

A Mother and Newborn with Brown Blood

2015· article· en· W2097897456 on OpenAlexaff
Mathew P. Estey, Gwen Clarke, Winnie Sia, E. J. Toor, Trefor Higgins

Bibliographic record

VenueClinical Chemistry · 2015
Typearticle
Languageen
FieldMedicine
TopicMethemoglobinemia and Tumor Lysis Syndrome
Canadian institutionsRoyal Alexandra HospitalUniversity of Alberta
Fundersnot available
KeywordsMedicine

Abstract

fetched live from OpenAlex

A 33-year-old woman of Indian origin presented for prenatal care at term. An ultrasound report from earlier in her pregnancy indicated complete placenta previa and placenta increta, which were confirmed by repeat ultrasound. She was admitted to the hospital for monitoring and delivery planning. On admission, brown vaginal spotting was noted on the patient's pad. Her nail beds and fingers were cyanotic, and a finger prick blood sample was rusty brown in appearance. Oxygen saturation by pulse oximetry on room air was 45% despite her appearing clinically well. She was otherwise asymptomatic. The patient's husband remarked that her family has “brown blood, not red,” noting that the patient's father, paternal grandfather, and sister also have brown blood but no clinical problems. Her 3-year-old daughter had a similar cyanotic appearance but was otherwise asymptomatic. Repeat oxygen saturation measurements by pulse oximetry consistently gave results between 40%–60%, and arterial blood P o2 was 95 mmHg. Methemoglobin measurement was attempted, but the cooximeter indicated “?Oximetry measuring error.” This was also confirmed by repeated measurements. Complete blood count results were as follows: hemoglobin, 12.5 g/dL (125 g/L; reference interval, 120–160 g/L); red blood cells (RBC),6 4.19 × 1012/L (reference interval, 3.80–5.20 × 1012/L); hematocrit (HCT), 38% (0.38; reference interval, 0.36–0.46); mean corpuscular volume (MCV), 90 fL (reference interval, 80–100 fL); mean corpuscular hemoglobin (MCH), 30 pg (reference interval, 26–35 pg); mean corpuscular hemoglobin concentration (MCHC), 33.3 g/dL (333 g/L; reference interval, 310–360 g/L); red cell width distribution (RDW), 13.2% (reference interval, <15.6%); platelets (PLT), 224 × 109/L (reference interval, 140–450 × 109/L); white blood cells (WBC) 9.6 × 109/L (reference interval, 4.0–11.0 × 109/L). ### QUESTIONS TO CONSIDER 1. What are causes of cyanosis and brown blood? 2. What additional laboratory tests could be useful in …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.783
Threshold uncertainty score0.321

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.334
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2015
Admission routes1
Has abstractyes

Explore more

Same venueClinical ChemistrySame topicMethemoglobinemia and Tumor Lysis SyndromeFrench-language works237,207