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Record W2099762535 · doi:10.1038/nature06341

Evolution of genes and genomes on the Drosophila phylogeny

2007· article· en· W2099762535 on OpenAlexaff
Charles F. Aquadro, K. Ravi Ram, Mariana F. Wolfner, Andrew G. Clark, Alex Wong, Nadia D. Singh, Anthony J. Greenberg, Melanie A. Huntley, Amanda M. Larracuente, Laura K. Sirot, Timothy B. Sackton, Daniel A. Barbash, Michael B. Eisen, Roger A. Hoskins, S Celniker, Adrianne B. Brand, Heather Ebling, Robert David, Tao Wei, Stephanie Bosak, Barry E. Garvin, Kevin McKernan, Marc Rubenfield, Jason M. Tsolas, Matthew J. Parisi, Erik Gustafson, David J. Saranga, Douglas R. Smith, Brendan McKernan, Sam Griffiths‐Jones, Casey Bergman, David Sturgill, Brian Oliver, Michael Parisi, Yu Zhang, Therese A. Markow, Thomas D. Watts, Carlos A. Machado, Luciano M. Matzkin, Roberta Kwok, Don Gilbert, Thomas C. Kaufman, Pouya Kheradpour, M. D. Rasmussen, M. Kellis, Leopold Parts, Alan Dupes, David B. Jaffe, Abderrahim Farina, Sante Gnerre, Nga Thi Thuy Nguyen, Terry Shea, Andrew Zimmer, Evan Mauceli, Elizabeth Ryan, Imane Bourzgui, Ngawang Sherpa, Tsering Wangdi, Norbu Dhargay, Marcia Lara, Jinlei Liu, Rebecca Reyes, Helen Vassiliev, Erica Anderson, Shangtao Liu, Tanya Mihova, Tamrat Negash, C. Strader, Teena Mehta, Cecil Rise, Will Brockman, Marc Azer, Choe Norbu, Andrew Hollinger, Stuart Degray, P Fritz, Christopher Patti, Pema Phunkhang, Adam Brown, James C. Meldrim, Lu Shi, Pasang Bachantsang, Jennifer L. Hall, Yeshi Lokyitsang, Annie Lui, Katie D'Aco, Pen MacDonald, Maura Costello, Amr Abdouelleil, Dawa Thoulutsang, Louis Meneus, Mieke Citroen, Jane Wilkinson, Kerstin Lindblad-Toh, Christina R. Gearin, Jerome W. Naylor, Eric Lander, Jean L. Chang, Dmitry Khazanovich, Daniel Bessette, Filip Rege, Sheila Fisher, Iain MacCallum, Aaron Berlin, Jill E. Falk, Valentine Mlenga, Todd Sparrow, Diana M. Shih, Tashi Lokyitsang, Adam Navidi, Chelsea D. Foley, Peter Kisner, Gary Gearin, Xiaohong Liu, Qing Yu, Leanne Hughes, Adam Wilson, Sharleen Grewal, J. Spaulding, Catherine Stone, Asha Kamat, Tsamla Tsamla, F Letendre, Missole Doricent, Vasilia Magnisalis, Alex Lipovsky, Danni Zhong, Barry O'Neill, Allen Alexander, Patrick A. Cooke, St Christophe Acer, Scott Anderson, Justin Abreu, Kunsang Dorjee, John Stalker, Pablo Álvarez, Birhane Hagos, Charles D. Matthews, Yama Thoulutsang, Tashi Bayul, Ira Topping, Erin E. Dooley, R Paul Levine, Passang Dorje, Leonid Boguslavskiy, Geneva Young, Anna Montmayeur, Kunsang Gyaltsen, Riza Daza, Manfred Grabherr, Lisa Chuda, Kerri Topham, Peter Rogov, Edward Grandbois, Kimberly Dooley, Eva Markiewicz, CheeWhye Chin, Tracey Honan, Seva Kashin, Andrew J. Barry, Dennis Friedrich, Robert Nicol, Kebede Maru, Sujaa Raghuraman, Patrick Cahill, William Lee, Sharon Stavropoulos, Tsering Wangchuk, Alville J. Collymore, Richard Elong, Krista Lance, T. Elizabeth Goode, Shailendra Yadav, Rachel Mittelman, Rakela Lubonja, Georgia Giannoukos, Atanas H. Mihalev, Nabil Hafez, Talene Thomson, Lynne Aftuck, Diallo Ferguson, Charlotte Henson, Susan Faro, Jamal Abdulkadir, Jonathan Butler, Nathaniel Novod, Senait Tesfaye, Lisa Zembek, A Franke, Yama Cheshatsang, Brian Hurhula, Nicole Stange-Thomann, Susan McDonough, Harindra Arachi, Niall J. Lennon, Leonidas Mulrain, William McCusker, Toby Bloom, Sampath Settipalli, Michael Weiand, Sahal Osman, Loryn Gadbois, Nyima Norbu, Brikti Abera, Andy H. Vo, Otero L. Oyono, Keenan Ross, Christina R. DeMaso, Oana Mihai, Ben Kanga, Jennifer Baldwin, Adal Abebe, Sheridon Channer, Joseph Graham, Jason Blye, Claude Bonnet, Boris Boukhgalter, Zac Zwirko, Michael Kleber, Magne Husby, Peter An, Margaret Priest, Monika D. Huard, Peili Zhang, William M Gelbart, Angela N. Brooks, Venky N. Iyer, Daniel A Pollard, Alfredo Villasanté, José P. Abad, María Méndez-Lago, Kristi L. Montooth, Dawn N. Abt, David Rand, Derek A. Wilson, Sarah A. Teichmann, Boris Adryan, Alejandro Sánchez‐Gracia, Carmen Segarra, Julio Rozas, Filipe Garrett Vieira, Montserrat Aguadé, Montserrat Papaceit, Albert J. Vilella, Wojciech Makałowski, Xu Mu, Stephen W. Schaeffer, Michael U. Mollenhauer, Gillian Halter, Valer Gotea, Hiroshi Akashi, Wyatt W. Anderson, Eva Freyhult, David H. Ardell, Jian Lü, Manyuan Long, J. Roman Arguello, Jerry A. Coyne, Rama S. Singh, Wilfried Haerty, Santosh Jagadeeshan, Carlo G. Artieri, Daniel Barker, Anastasia Gardiner, Michael G. Ritchie, Paolo Barsanti, Damiano Porcelli, Corrado Caggese, Philip Batterham, Charles Robin, Robert T. Good, Samuel Gross, Serafim Batzoglou, Charles H. Langley, Carolyn S. McBride, Dave Begun, Temple F. Smith, Charles E. Chapple, Roderic Guigò, Anat Caspi, Ian Holmes, Robert K. Bradley, Gabriel Wu, Michael R. Brent, Randall H. Brown, Roger K. Butlin, Brian R. Calvi, Leonardo Barbosa Koerich, Antonio Bernardo Carvalho, Sergio Castrezana, Lior Pachter, Sourav Chatterji, Sandra W. Clifton, Lucinda Fulton, Richard K. Wilson, John Spieth, Asif Chinwalla, LaDeana Hillier, Robert S. Fulton, Jennifer Godfrey, Patrick Minx, Kim D. Delehaunty, Amy Denise Reily, Alberto Civetta, Lisa Levesque, Ana Llopart, Josep M. Comeron, Bryant McAllister, James C. Costello, Mira Han, Jennifer Daub, Michael C. Schatz, Adam M. Phillippy, Steven L. Salzberg, Mihai Pop, Stephen M. Mount, Arthur L. Delcher, Kevin A. Edwards, Thomas Eickbush, Deborah E. Stage, Jay D. Evans, Sven Findeiß, Sudhir Kumar, Alan Filipski, Sonja J. Prohaska, Ana Cristina Lauer Garcia, Vera Lúcia da Silva Valente, Mohamed A. F. Noor, David Garfield, Laura K Reed, Greg Gibson, Brenton Gravely, Peter D. Keightley, Daniel L. Halligan, Robert L. Strausberg, Karin Remington, Brian P. Walenz, Aaron L. Halpern, Granger Sutton, J. Craig Venter, Justin Johnson, Granger G. Sutton, Eli Venter, Ewen F. Kirkness, Angie S. Hinrichs, Jakob Skou Pedersen, Melissa J. Hubisz, Dan Hultmark, Corbin D. Jones, William R. Jeck, William Chester Jordan, Chris D. Smith, Muneo Matsuda, Hajime Sato, Eiko Kataoka, Karsten Kristiansen, Ruiqiang Li, Rod A. Wing, Dave Kudrna, Nicholas Sisneros, Meizhong Luo, Elena R. Lozovsky, Rob J. Kulathinal, Stuart J. Newfeld, Patrick O'Grady, Richard T. Lapoint, Brian P. Lazzaro, Gane Ka‐Shu Wong, Marta Puig, Mar Marzo, Alfredo Ruíz, Eugene W. Myers, Bárbara Negre, Rasmus Nielsen

Bibliographic record

VenueNature · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsUniversity of AlbertaUniversity of WinnipegArtificial Intelligence in Medicine (Canada)McMaster University
FundersEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentU.S. National Library of MedicineNational Institute of General Medical SciencesNational Human Genome Research InstituteBiotechnology and Biological Sciences Research CouncilNational Institutes of HealthNatural Environment Research CouncilSight Research UKBroad Institute
KeywordsBiologyGenomeEvolutionary biologyDrosophila virilisDrosophila pseudoobscuraDrosophila (subgenus)Human evolutionary geneticsGeneticsPhylogenetic treeDrosophila melanogasterPhylogeneticsMelanogasterComparative genomicsGeneGenomics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.228
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2,113
Published2007
Admission routes1
Has abstractno

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