Protective Effect of Total Flavones of Buckwheat Flowers on Carbon Tetrachloride-induced Hepatic Impairment
Why this work is in the frame
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Bibliographic record
Abstract
Objective: The protective effect and possible mechanism of total flavones of buckwheat flowers (TFBF) onexperimental hepatic impairment in mice were studied. Methods: The hepatic impairment model of mice was inducedby injecting carbon tetrachloride (CCl4) subcutaneously (sc) every 4 days for 7 times. Meanwhile, mice in the twotreatment groups were given TFBF at dosages of 0.04 g•kg-1•d-1 and 0.02 g•kg-1•d-1 respectively through intragastric (ig)injection, and mice in the positive control group were treated with methionine (MET) by contrast. Next the day CCl4was lastly injected, half the mice were killed. The contents of alanine aminotransferase (ALT) in serum and ALT,superoxidase dismutase (SOD), glutathione (GSH), malonaldehyde (MDA), triglyceride (TG), total cholesterol (TC) inliver tissue, the liver indexes (LI), and the hepato-pathologic changes of the mice were examined. The rest mice weregiven identical treatment for another 2 weeks. Results: TFBF could inhibit the rising of serum ALT, liver MDA, TG, TC,LI, and the lowering of liver SOD and GSH in CCl4-induced hepatic impairment mice. It could obviously ease thehepato-pathologic damages as well. Conclusion: TFBF could effectively protect the hepatic impairment in CCl4-inducedmice.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it