Tissue Oxygenation in Men and Women During Repeated-Sprint Exercise
Bibliographic record
Abstract
PURPOSE: To understand the role of O2 utilization in the sex differences of fatigue during intermittent activity, we compared the cerebral (prefrontal lobe) and muscle (vastus lateralis) oxygenation of men and women during repeated-sprint exercise (RSE). METHODS: Ten men and 10 women matched for initial-sprint mechanical work performed ten, 10 s cycle sprints (with 30 s of rest) under normoxic (NM: 21% FIO2) and acute hypoxic (HY: 13% FIO2) conditions in a randomized single-blind and crossover design. Mechanical work was calculated and arterial O2 saturation (SpO2) was estimated via pulse oximetry during every sprint. Cerebral and muscle oxy- (O2Hb) and deoxy-hemoglobin (HHb) were monitored continuously by near-infrared spectroscopy. RESULTS: Compared with NM, work decrement was accentuated (P = 0.01) in HY for both men (-16.4 ± 10.3%) and women (-16.8 ± 9.0%). This was associated with lower SpO2 and lower cerebral Δ[O2Hb] in both sexes (-13.6 ± 7.5%, P = .008, and -134.5 ± 73.8%, P = .003, respectively). These HY-induced changes were nearly identical in these men and women matched for initial-sprint work. Muscle Δ[HHb] increased 9-fold (P = .009) and 5-fold (P = .02) in men and women, respectively, and plateaued. This muscle deoxygenation was not exacerbated in HY. CONCLUSIONS: Results indicate that men and women matched for initial-sprint work experience similar levels of fatigue and systemic, cerebral, and peripheral adjustments during RSE performed in NM and HY. These data suggest that cerebral deoxygenation imposes a limitation to repeated-sprint performance.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".