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Record W2105146834 · doi:10.1371/journal.pone.0009515

A Scoping Review of Strategies for the Prevention of Hip Fracture in Elderly Nursing Home Residents

2010· review· en· W2105146834 on OpenAlexafffund
Anna M. Sawka, Nofisat Ismaila, Ann Cranney, Lehana Thabane, Monika Kastner, Amiram Gafni, Linda J. Woodhouse, Richard Crilly, Angela M. Cheung, Jonathan D. Adachi, Robert G. Josse, Αλεξάνδρα Παπαϊωάννου

Bibliographic record

VenuePLoS ONE · 2010
Typereview
Languageen
FieldMedicine
TopicBone health and osteoporosis research
Canadian institutionsSt. Joseph’s Healthcare HamiltonSt. Michael's HospitalWestern UniversitySunnybrook Health Science CentreHealth Sciences CentreOttawa HospitalHamilton Health SciencesUniversity of TorontoUniversity Health NetworkMcMaster University
FundersCanadian Institutes of Health ResearchSanofiAmgenPfizerUniversity of TorontoEli Lilly and Company
KeywordsHip fractureMedicinePsychological interventionPhysical therapyRandomized controlled trialVitamin D and neurologyOsteoporosisPopulationGerontologyInternal medicineNursingEnvironmental health

Abstract

fetched live from OpenAlex

BACKGROUND: Elderly nursing home residents are at increased risk of hip fracture; however, the efficacy of fracture prevention strategies in this population is unclear. OBJECTIVE: We performed a scoping review of randomized controlled trials of interventions tested in the long-term care (LTC) setting, examining hip fracture outcomes. METHODS: We searched for citations in 6 respective electronic searches, supplemented by hand searches. Two reviewers independently reviewed all citations and full-text papers; consensus was achieved on final inclusion. Data was abstracted in duplicate. FINDINGS: We reviewed 22,349 abstracts or citations and 949 full-text papers. Data from 20 trials were included: 7--vitamin D (n = 12,875 participants), 2--sunlight exposure (n = 522), 1--alendronate (n = 327), 1--fluoride (n = 460), 4--exercise or multimodal interventions (n = 8,165), and 5--hip protectors (n = 2,594). Vitamin D, particularly vitamin D(3) > or = 800 IU orally daily, reduced hip fracture risk. Hip protectors reduced hip fractures in included studies, although a recent large study not meeting inclusion criteria was negative. Fluoride and sunlight exposure did not significantly reduce hip fractures. Falls were reduced in three studies of exercise or multimodal interventions, with one study suggesting reduced hip fractures in a secondary analysis. A staff education and risk assessment strategy did not significantly reduce falls or hip fractures. In a study underpowered for fracture outcomes, alendronate did not significantly reduce hip fractures in LTC. CONCLUSIONS: The intervention with the strongest evidence for reduction of hip fractures in LTC is Vitamin D supplementation; more research on other interventions is needed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.025
metaresearch head score (Gemma)0.087
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.025
Threshold uncertainty score0.134

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0250.087
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0090.009
Bibliometrics0.0210.019
Science and technology studies0.0020.001
Scholarly communication0.0050.004
Open science0.0030.003
Research integrity0.0040.002
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.183
GPT teacher head0.460
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations40
Published2010
Admission routes2
Has abstractyes

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