MétaCan
← all works

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

2010· article· en· 739 citations· W2109715726 on OpenAlex· 10.1038/nbt.1682

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.019
GPT teacher head0.369
Teacher spread
0.350 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Biotechnology
Topic
Epigenetics and DNA Methylation
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
BC Cancer Agency
Funders
National Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthNational Cancer InstituteNational Institute of General Medical SciencesNational Institute on Drug AbuseNational Institute of Environmental Health SciencesUniversity of Waterloo
Keywords
Methylated DNA immunoprecipitationBisulfite sequencingIllumina Methylation AssayDNA methylationBiologyEpigeneticsCpG siteGenomic imprintingGeneticsComputational biologyDNA sequencingDifferentially methylated regionsDeep sequencingGenomeGeneGene expression
Has abstract in OpenAlex
no