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Metagenomic Analysis of Uterine Microbiota in Postpartum Normal and Endometritic Water Buffaloes (Bubalus bubalis)

2013· article· en· W2109785566 on OpenAlexvenueno aff
K. Onnureddy, Y. Vengalrao, T. K. Mohanty, Dheer Singh

Bibliographic record

VenueJournal of Buffalo Science · 2013
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicReproductive Physiology in Livestock
Canadian institutionsnot available
FundersDepartment of Biotechnology, Ministry of Science and Technology, India
KeywordsBiologyFusobacteriaBacteroidetesFirmicutesPopulationMicrobiologyProteobacteriaBubalus16S ribosomal RNAGeneticsBacteria

Abstract

fetched live from OpenAlex

In Indian subcontinent the water buffalo (Bubalus bubalis) is one of the important livestock animals. As in cows, postpartum infection like endometritis in dairy buffaloes is major cause for the economic loss in the dairy industries. Till date, there is no study regarding metagenomic analysis of bacterial population of postpartum endometritic buffaloes. The purpose of this study was to identify and compare the uterine bacterial composition in normal and endometritic postpartum buffaloes using 16S rDNA cloning, which was a type of culture-independent methods. A total of 151 cloned plasmids for 16S rDNA from both normal and endometritic uterine samples were sequenced. Cloning library of 16S rDNA revealed clear cut difference between bacterial populations of normal and endometritic postpartum buffaloes. Cloned sequences were assigned to five major groups and one uncultured group. The five major groups include- Bacteroidetes, Firmicutes, Fusobacteria, Proteobacteria, and Tenericutes. Major cloned sequences from normal status endometrium were affiliated to phylum Proteobacteria, and most of the sequences showed high degree of similarity with bacteria Haemophilus felis. Most of the sequences from cloned library of endometritic status samples were affiliated to phylum Proteobacteria and Tenericutes. The most prevalent bacteria found in endometritic samples were Psychrobacter sp. PRwf-1, Psychrobacter pulmonis, Ureaplasma diversum strain T95 and Ureaplasma diversum strain A417. A major number of cloned sequences from both normal and endometritic samples were assigned to uncultured group. The present data showed bacterial population of postpartum normal and endometritic buffaloes and also described the presence of various types microbiota in uterine samples.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.234
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2013
Admission routes1
Has abstractyes

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