MétaCan
Menu
Back to cohort
Record W2110396304 · doi:10.1073/pnas.1118760109

Y-chromosome analysis reveals genetic divergence and new founding native lineages in Athapaskan- and Eskimoan-speaking populations

2012· article· en· W2110396304 on OpenAlex
Matthew C. Dulik, Amanda C. Owings, Jill B. Gaieski, Miguel G. Vilar, Alestine Andre, Crystal Lennie, Mary Adele Mackenzie, Ingrid Kritsch, Sharon Snowshoe, Ruth Wright, James P. Martin, Nancy Gibson, T. Daniel Andrews, Theodore G. Schurr, Syama Adhikarla, Christina Adler, Elena Balanovska, Oleg Balanovsky, Jaume Bertranpetit, Andrew Clarke, David Comas, Alan Cooper, Clio S. I. Der Sarkissian, ArunKumar GaneshPrasad, Wolfgang Haak, Marc Haber, Angela Hobbs, Asif Javed, Jin Li, Matthew E. Kaplan, Shilin Li, Begoña Martínez‐Cruz, Elizabeth Matisoo‐Smith, Marta Melé, Nirav Merchant, R. John Mitchell, Laxmi Parida, Ramasamy Pitchappan, Daniel E. Platt, Lluís Quintana‐Murci, Colin Renfrew, Daniela R. Lacerda, Ajay K. Royyuru, Fabrício R. Santos, Himla Soodyall, David F. Soria Hernanz, Pandikumar Swamikrishnan, Chris Tyler‐Smith, Arun Varatharajan Santhakumari, Pedro Paulo Vieira, R. Spencer Wells, Pierre Zalloua, Janet Ziegle

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueProceedings of the National Academy of Sciences · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicForensic and Genetic Research
Canadian institutionsCanadian HeritageTlicho Community Services AgencyInuvialuit Regional CorporationNunavut Research Institute
FundersUniversity of PennsylvaniaNational Geographic Society
KeywordsBiologyPopulationEvolutionary biologyGeneticsDivergence (linguistics)Y chromosomeDemographyLinguisticsSociologyGene

Abstract

fetched live from OpenAlex

For decades, the peopling of the Americas has been explored through the analysis of uniparentally inherited genetic systems in Native American populations and the comparison of these genetic data with current linguistic groupings. In northern North America, two language families predominate: Eskimo-Aleut and Na-Dene. Although the genetic evidence from nuclear and mtDNA loci suggest that speakers of these language families share a distinct biological origin, this model has not been examined using data from paternally inherited Y chromosomes. To test this hypothesis and elucidate the migration histories of Eskimoan- and Athapaskan-speaking populations, we analyzed Y-chromosomal data from Inuvialuit, Gwich'in, and Tłįch populations living in the Northwest Territories of Canada. Over 100 biallelic markers and 19 chromosome short tandem repeats (STRs) were genotyped to produce a high-resolution dataset of Y chromosomes from these groups. Among these markers is an SNP discovered in the Inuvialuit that differentiates them from other Aboriginal and Native American populations. The data suggest that Canadian Eskimoan- and Athapaskan-speaking populations are genetically distinct from one another and that the formation of these groups was the result of two population expansions that occurred after the initial movement of people into the Americas. In addition, the population history of Athapaskan speakers is complex, with the Tłįch being distinct from other Athapaskan groups. The high-resolution biallelic data also make clear that Y-chromosomal diversity among the first Native Americans was greater than previously recognized.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.174
Threshold uncertainty score0.196

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.365
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it