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Record W2110535520 · doi:10.1038/ng.760

Common variants in ZNF365 are associated with both mammographic density and breast cancer risk

2011· review· en· W2110535520 on OpenAlexaff
Sara Lindström, Celine M. Vachon, Jingmei Li, Jajini S. Varghese, Deborah J. Thompson, Ruth Warren, Judith Brown, Jean Leyland, Tina Audley, Nicholas J. Wareham, Ruth J. F. Loos, Andrew D. Paterson, Johanna M. Rommens, Darryl Waggott, Lisa J. Martin, Christopher G. Scott, V. Shane Pankratz, Susan E. Hankinson, Aditi Hazra, David J. Hunter, John L. Hopper, Melissa C. Southey, Stephen J. Chanock, Isabel dos‐Santos‐Silva, Jianjun Liu, Louise Eriksson, Fergus J. Couch, Jennifer Stone, Carmel Apicella, Kamila Czene, Peter Kraft, Per Hall, Douglas F. Easton, Norman F. Boyd, Rulla M. Tamimi

Bibliographic record

VenueNature Genetics · 2011
Typereview
Languageen
FieldMedicine
TopicGlobal Cancer Incidence and Screening
Canadian institutionsOntario Institute for Cancer ResearchLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalUniversity of TorontoPublic Health OntarioHospital for Sick Children
FundersNational Cancer InstituteCancer Research UK
KeywordsBreast cancerMAMMOGRAPHIC DENSITYGenome-wide association studyBiologyBody mass indexRisk factors for breast cancerGenetic associationOncologyLocus (genetics)MammographyMeta-analysisCancerGeneticsInternal medicineSingle-nucleotide polymorphismMedicineGenotypeGeneEndocrinology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesResearch integrity
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.398
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.332
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations124
Published2011
Admission routes1
Has abstractno

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