Glioblastoma Multiforme and Ascending Weakness
Bibliographic record
Abstract
An 18-year-old man with a known glioblastoma multiforme, previously treated with de-bulking, chemotherapy, radiation and steroids, underwent a repeat craniotomy after presenting with several days of intractable vomiting and headache. Postoperatively, he developed progressive delirium, bilateral sixth and seventh nerve palsies, dysphagia and ascending weakness of the upper and lower limbs. Within five postoperative days, he was quadraparetic, areflexic and had marked extraocular muscle and facial weakness, dysphagia, dysphonia and respiratory muscle weakness. The patient was started empirically on intravenous immunoglobulin for suspected Guillain-Barré syndrome (GBS). The following day, lumbar puncture demonstrated elevated protein (1.96g/l; normal <0.45), and a reduced glucose (0.5 mmol/l) and elevated red (4125x106 per litre) and white cell (214x106 per litre) counts in the cerebrospinal fluid (the red cells were felt to be related to surgery). The cell differential included 69% neutrophils, 3% lymphocytes, 15% monocytes and 13% blast-like cells. Gram stains and cultures of the cerebrospinal fluid were negative.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".