The functional microstructure of tendon collagen revealed by high‐field MRI
Bibliographic record
Abstract
T2 was used in this study to assess tendon microstructure. Two unloaded digital extensor tendons were bent such that their long axes were imaged throughout 180° with respect to B0. T2-weighted images reveal periodic banding (∼200 μm) when tendons were oriented at ±55° with respect to B0. Five pairs of tendons were used to study the influence of load on T2W MRI: one tendon of each pair was loaded with a 7.8-N mass, and both tendons were fixed in formalin then imaged at 55° to B0. MRI banding was present in the unloaded, but not loaded, tendons. In unloaded tendons, polarized-light microscopy revealed collagen crimp with a periodicity similar to MRI. In loaded tendons, there was a strain-induced extinction of periodicity on both MRI and polarized-light microscopy. These studies confirm that crimp is detectable by high-field MRI and could serve as an in vivo index of physiological strains in collagenous tissues.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".