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Record W2114832664 · doi:10.1148/radiol.2015142779

Pitfalls of Systematic Reviews and Meta-Analyses in Imaging Research

2015· review· en· W2114832664 on OpenAlexaff
Matthew D. F. McInnes, Patrick M. Bossuyt

Bibliographic record

VenueRadiology · 2015
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsMedicineSystematic reviewPoolingPsychological interventionMedical physicsPublication biasMeta-analysisQuality (philosophy)MEDLINEManagement scienceData sciencePathologyComputer scienceArtificial intelligenceEpistemology

Abstract

fetched live from OpenAlex

Systematic reviews of imaging research represent a tool to better understand test accuracy or the efficacy of interventions. Like any type of research, appropriate methods must be applied to optimize quality. The purpose of this review is to outline common pitfalls in performing systematic reviews of imaging research, with a focus on challenges particular to performing reviews of diagnostic accuracy studies. The following challenges are highlighted: posing relevant review questions, conducting comprehensive literature searches, assessing for bias in included studies, testing for heterogeneity and publication bias, pooling results across studies, and forming appropriate conclusions. By guiding authors on how to overcome these, the hope is that published reviews in imaging research will be of higher quality and have a positive impact on clinical practice. In addition, the review aims to educate readers of reviews so they become aware of crucial elements of systematic reviews that could bias review results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearch
Domain: Methods · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Not applicablehigh
gptMetaresearch
Domain: Methods · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Other designhigh
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.553
metaresearch head score (Gemma)0.219
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Meta-epidemiology (broad), Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.797
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.5530.219
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0760.009
Bibliometrics0.0030.004
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0040.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.987
GPT teacher head0.741
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

Metaresearch

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designNot applicable · Other design
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations97
Published2015
Admission routes1
Has abstractyes

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