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Record W2116689979 · doi:10.5539/ijb.v1n2p101

Isolation and Characterization of a Silkworm cDNA Encoding a Protein Homologous to the 14kDa Protein of Bovine Ubiquinol-cytochrome C Reductase

2009· article· en· W2116689979 on OpenAlexvenueno aff
Guangwei Xing, Jinghong Xing, Suhua Wang

Bibliographic record

VenueInternational Journal of Biology · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInsect Resistance and Genetics
Canadian institutionsnot available
Fundersnot available
KeywordsProtein subunitBiochemistryBiologyReductaseComplementary DNAUbiquinolHomology (biology)Cytochrome cGenePeptide sequenceProtein primary structureMolecular biologyCytochrome bOpen reading frameCoenzyme Q – cytochrome c reductasePhylogenetic treeEnzymeMitochondrion

Abstract

fetched live from OpenAlex

In this study, we characterized the small subunit of ubiquinol-cytochrome C reductase (Bmuccr) of the silkwormBombyx mori, a model insect of Lepidopteron species. The Bmuccr gene covers a 1.4 kb genome region and contains 3exons. The ORF contained 354bp and encoded 117 amino acid residues, which shares 69% overall amino acid sequenceidentities with the subunit VII of ubiquinol-cytochrome C reductase from bovine. Phylogenetic tree showed Bmuccr hadhigh homology with T. castaneum homologous. The multiple sequence alignment of 16 subunit VII homologues showsthat Bmuccr is very hydrophilic, has a characteristic charge distribution, and has a high helical content. Expressionanalysis indicated that Bmuccr was highly expressed in larva stage and was down-regulated in embryos stage and adultstage of silkworm. The tissue-specific expression indicated Bmuccr had high-expression level in tissues that consumeoxygen. The analysis of domain structure of this protein suggested that it might be involved in correct assembly of thecytochrome bcl complex. Definition of the homologous of bovine subunit VII of ubiquinol-cytochrome C reductaseshould facilitate further analysis of structure/function relationships of silkworm cytochrome bcl complex.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.242

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.257
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2009
Admission routes1
Has abstractyes

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