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The Effect of Fish Oil Supplement on Serum Antioxidant Level in Patient with Rheumatoid Arthritis

2013· article· en· W2118338743 on OpenAlexvenueno aff
Sousan Kolahi, Amir Ghorbanihaghjo, Alireza Khabbazi, Mehrzad Hajialilo, Hale Farzin

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2013
Typearticle
Languageen
FieldHealth Professions
TopicDiverse Scientific Research Studies
Canadian institutionsnot available
Fundersnot available
KeywordsAntioxidantRheumatoid arthritisFish oilSuperoxide dismutaseMedicineOxidative stressArthritisGlutathione peroxidasePlaceboInternal medicineImmunologyPharmacologyPhysiologyChemistryBiochemistryFish <Actinopterygii>BiologyPathologyFishery

Abstract

fetched live from OpenAlex

Purpose:Rheumatoid arthritis (RA) is a common autoimmune disease characterized by inflammation and over-growth of the synovium. RA is accompanied with increased levels of free radical and stress oxidative. In recent years, there has been an increasing interest in nutritional factors on disease and autoimmune system. More recently literatures have emerged that offers contradictory findings about fish oil on antioxidant levels. So far however, there has been little discussion about fish oil as antioxidant on Rheumatoid arthritis. This paper will focus on effect of fish oil over serum antioxidant levels and activity disease of RA.Methods: A randomized double blinded control trial 90 patients from a population of Rheumatoid Arthritis who were selected. Forty five patients received Fish oil (FO) (1gr /day) in addition of conventional therapy for RA versus 45 patients received placebo. And serum levels of plasma antioxidant capacity (TAC) and the activity of superoxide dismutase (SOD) and Glutathione peroxides (GPX) were measured.Results:There was no statistically difference between groups in plasma antioxidant capacity and the activity of superoxide dismutase, Glutathione peroxides. There weren’t any correlation among DAS and antioxidant serum levels.Conclusion: The findings emerging from the present inquiry suggested that FO with 1 gram daily dose didn’t have effect on serum antioxidant level and activity of disease in RA.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.423
Teacher spread0.346 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2013
Admission routes1
Has abstractyes

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