Bibliographic record
Abstract
Beyond depression's impact on life quality, it is associated with both the incidence of coronary heart disease (CHD) and its prognosis. Depression is three times more common in CHD patients than in the general community. It is independently associated with at least a doubling in risk of subsequent cardiac events. Studies also show that it may precede the development of clinically evident CHD by many years. The mechanisms linking depression and CHD are currently unknown and likely to be complex. In addition to behavioral factors, changes in autonomic regulation, vascular disease of the brain, subchronic inflammation, reduced omega-3 free fatty acid levels, and enhanced platelet responsiveness may all be involved. Only one large clinical trial has attempted to alter CHD prognosis by treating depression. It succeeded in producing a small, but significant reduction in depression symptoms, but had no impact on subsequent CHD events. While debate continues about the causal relationship between CHD and depression, the best treatment strategy to improve prognosis in depressed CHD patients remains intensive modification of standard CHD risk factors in combination with treatment of depression to improve life quality.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".