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Record W2119596187

Herbal tea in the treatment of diabetes mellitus.

2000· article· en· W2119596187 on OpenAlexaffabout
Edmond A. Ryan, Sharleen Imes, Clarissa Wallace, Steven R. Jones

Bibliographic record

VenuePubMed · 2000
Typearticle
Languageen
FieldMedicine
TopicTea Polyphenols and Effects
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsFructosamineMedicinePlaceboDiabetes mellitusMealInternal medicineArea under the curveCaffeineTraditional medicineGastroenterologyEndocrinology
DOInot available

Abstract

fetched live from OpenAlex

OBJECTIVE: To evaluate the effects of a native herbal tea in patients with type 2 diabetes. DESIGN: Randomized, placebo-controlled, single-blind study. SETTING: The Metabolic Centre at the University of Alberta Hospitals. SUBJECTS: Forty volunteers with type 2 diabetes. INTERVENTIONS: After a 1 month "run-in" period, subjects drank 250 mL/d of either the herbal tea or a placebo tea for 10 days, and were followed up for a further 4 weeks. OUTCOME MEASURES: A responder analysis defined as a 10% change in mean blood glucose levels based on 4 capillary glucose readings daily. Secondary end points included changes in HbA1c, fructosamine and response to a meal challenge using Ensure. RESULTS: The responder analysis showed no benefit from the herbal tea. Fructosamine levels before and after tea therapy decreased significantly in both study groups. Mean HbA1c levels and incremental areas under the glucose curve (AUC) in the meal challenge did not change in either study group. These data were reanalysed in hyperglycemic subjects with HbA1c levels greater than 120% of normal. The responder analysis and HbA1c levels did not change in either group. Mean (and standard deviation) fructosamine levels, before and after tea therapy, were significantly lower in the herbal tea group than in the placebo tea group (361 [98] versus 338 [100] micromol/L, p < 0.01 compared with 338 [60] versus 323 [49] micromol/L, p = 0.08). In the hyperglycemic subgroup the mean AUC during the meal challenge, before versus after tea therapy, was 776 (369) versus 639 (331) mmol/L (p = 0.22) in the herbal tea group and 433 (125) versus 420 (173) mmol/L (p = 0.90) in the placebo group. CONCLUSIONS: Although the responder analysis failed to show an effect of the herbal tea, the data suggest there may be a short-term benefit from the tea in subjects with poor glycemic control.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.954
Threshold uncertainty score0.138

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.228
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2000
Admission routes2
Has abstractyes

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