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Invited Article: Practice parameters and technology assessments

2008· article· en· W2122843283 on OpenAlexfundno aff
Gary Gronseth, Jacqueline A. French

Bibliographic record

VenueNeurology · 2008
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsnot available
FundersEisaiGlaxoSmithKlineValeant Pharmaceuticals InternationalPfizer
KeywordsCarotid endarterectomyMedicineGuidelineLamotrigineStenosisEndarterectomyEpilepsyPsychiatryRadiology

Abstract

fetched live from OpenAlex

A neurologist is evaluating a patient in the office after the patient reported a 5-minute episode of blindness of the right eye and clumsiness of the left arm. She orders a carotid ultrasound that reveals some carotid plaques, with a <50% stenosis of the right and left carotid artery. She consults a vascular surgeon, who recommends immediate right carotid endarterectomy. Before she proceeds, she checks the American Academy of Neurology (AAN) Web site to see if there are any relevant practice parameters on carotid endarterectomy. She discovers that endarterectomy is not recommended for her patient.1 Armed with this definitive information, she discusses treatment options with the patient and the surgeon and prescribes antiplatelet therapy, as recommended in the guideline. In light of her recent positive experience with guidelines, she is quick to check the AAN Web site when seeing her next patient, a child who has a new diagnosis of absence seizures. Hoping to receive guidance in selecting the proper first therapy, she finds a guideline on treatment of the patient with newly diagnosed seizures.2 The only recommended therapy is lamotrigine (Level B), and she selects this treatment for her patient. The child continues to have seizures, so she asks an epileptologist for an opinion. The epileptologist questions why she did not use ethosuximide, which is considered first-line therapy for childhood absence epilepsy.3 She switches the child to ethosuximide, wondering where she and the guideline went wrong. These two scenarios illustrate the proper use and the limitations of guidelines. Guidelines are often misunderstood relative to their implications and purpose. As guidelines become an ever-increasing presence on the healthcare landscape, for neurologists as well as in other areas of medicine, it is important to explain what AAN guidelines are and what they are not. An AAN practice parameter …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.607
Threshold uncertainty score0.853

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.322
GPT teacher head0.442
Teacher spread0.120 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations90
Published2008
Admission routes1
Has abstractyes

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