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Testing the Equivalence of Survival Distributions using PP- and PPP-Plots

2014· article· en· W2127310938 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueInternational Journal of Statistics in Medical Research · 2014
Typearticle
Languageen
FieldComputer Science
TopicBayesian Methods and Mixture Models
Canadian institutionsnot available
Fundersnot available
KeywordsStatisticsMathematicsWilcoxon signed-rank testEquivalence (formal languages)Null hypothesisHazard ratioLog-rank testPlot (graphics)Survival analysisPopulationHazardMann–Whitney U testDemographyDiscrete mathematicsConfidence intervalBiology

Abstract

fetched live from OpenAlex

This paper discusses the use of PP-plots for survival distributions where for a pair of survival distributions, one is plotted against the other. This is another way of visualizing the nature of the relationship between the two survival distributions along with typical Kaplan-Meier plots. For three survival distributions, the PPP-plot is introduced where the survival distributions are plotted against each other in three-dimensions. At the population level, measures of divergence between distributions are introduced based on areas and lengths associated with the PP- and PPP- plots. At the sample level, two test statistics are defined, based on these areas and lengths, to test the null hypothesis of equivalent survival curves. A simulation exercise showed that, overall, the new tests are worthy competitors to the log-rank and Wilcoxon tests and also to a Levine-type test and a Kolmogorov-Smirnov type test for the case of crossing survival curves. The paper also shows how the PP-plot can be used to estimate the hazard ratio and to assess the ratio of hazard functions if proportional hazards are not appropriate. Finally, the methods introduced are illustrated on two cancer data sets

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.023
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.544
Threshold uncertainty score0.985

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.023
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.174
GPT teacher head0.478
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it