MétaCan
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Effect of Azithromycin on Pulmonary Function in Patients With Cystic Fibrosis Uninfected With <emph type="ital">Pseudomonas aeruginosa</emph><subtitle>A Randomized Controlled Trial</subtitle>

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

About CanadaIts subject is Canada, wherever its authors sit.

No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
Randomized trialNon-randomized trial
Classifier consensus
Randomized trial
Teacher imitation scores

Codex

Randomized trial1.000
Other design0.338
Bench or experimental0.005
Non-randomized trial0.001
Metaresearch0.001
Research integrity0.001
Not applicable0.001
Meta-epidemiology (narrow)0.000
Observational0.000
Meta-analysis0.000
Theoretical or conceptual0.000
Simulation or modelling0.000
Scholarly communication0.000
Meta-epidemiology (broad)0.000
Case report0.000
Bibliometrics0.000
Systematic review0.000
Qualitative0.000
Science and technology studies0.000
Open science0.000

Gemma

Randomized trial0.996
Observational0.015
Not applicable0.006
Bench or experimental0.004
Non-randomized trial0.004
Metaresearch0.003
Simulation or modelling0.001
Meta-analysis0.001
Research integrity0.001
Case report0.000
Science and technology studies0.000
Theoretical or conceptual0.000
Meta-epidemiology (narrow)0.000
Bibliometrics0.000
Systematic review0.000
Qualitative0.000
Meta-epidemiology (broad)0.000
Scholarly communication0.000
Open science0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.004
GPT teacher head0.238
Teacher spread
0.234 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Azithromycin is recommended as therapy for cystic fibrosis (CF) patients with chronic Pseudomonas aeruginosa infection, but there has not been sufficient evidence to support the benefit of azithromycin in other patients with CF.

To determine if azithromycin treatment improves lung function and reduces pulmonary exacerbations in pediatric CF patients uninfected with P. aeruginosa. DESIGN, SETTING, AND PARTICIPANTS: A multicenter, randomized, double-blind placebo-controlled trial was conducted from…

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