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Record W2129733357 · doi:10.1186/s13059-014-0430-2

Building a data sharing model for global genomic research

2014· article· en· W2129733357 on OpenAlexafffund
Patricia Kosseim, Edward S. Dove, Carman Baggaley, Eric M. Meslin, Fred H. Cate, Jane Kaye, Jennifer R. Harris, Bartha Maria Knoppers

Bibliographic record

VenueGenome biology · 2014
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsMcGill UniversityOffice of the Privacy Commissioner of Canada
FundersInstitute of GeneticsNational Center for Research ResourcesGenome CanadaCanadian Institutes of Health ResearchNational Cancer InstituteU.S. Department of Health and Human ServicesNational Institutes of HealthWellcome Trust
KeywordsData sharingBiologyMechanism (biology)Human geneticsData scienceGenomic informationGenome BiologyComputational biologyGenomicsComputer scienceGeneticsGenomeGene

Abstract

fetched live from OpenAlex

Data sharing models designed to facilitate global business provide insights for improving transborder genomic data sharing. We argue that a flexible, externally endorsed, multilateral arrangement, combined with an objective third-party assurance mechanism, can effectively balance privacy with the need to share genomic data globally.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.058
metaresearch head score (Gemma)0.049
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Open science
Consensus categoriesnone
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.995
Threshold uncertainty score0.307

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0580.049
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.003
Science and technology studies0.0040.009
Scholarly communication0.0160.031
Open science0.0050.020
Research integrity0.0070.008
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.869
GPT teacher head0.689
Teacher spread0.181 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainReproducibility
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations62
Published2014
Admission routes2
Has abstractyes

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