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Haemocytes of larval <i>Malacosoma disstria</i> (Lepidoptera: Lasiocampidae) and factors affecting their adhesion to glass slides

2005· article· en· W2129773451 on OpenAlexafffund
Paschalis Giannoulis, Cory L. Brooks, Vladislav Gulii, Gary B. Dunphy

Bibliographic record

VenuePhysiological Entomology · 2005
Typearticle
Languageen
FieldImmunology and Microbiology
TopicInvertebrate Immune Response Mechanisms
Canadian institutionsMcGill University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBiologyActivator (genetics)CalciumLepidoptera genitaliaMicrobiologyMolecular biologyInstarBiochemistryProtein kinase ABotanyEnzymeLarvaReceptorMaterials science

Abstract

fetched live from OpenAlex

Abstract. Although haemocytes of the forest pest lepidopteran, Malacosoma disstria (L.) have been studied, the physico‐chemical factors and signalling components affecting their non‐self activities have not been examined. Both the ameboid and stellate forms of plasmatocytes and the granular cells from fifth‐instar larvae adhere best to glass slides with phosphate‐buffered saline (PBS), with maximum granular cell binding within a pH range of 6.0–7.0 and plasmatocyte binding at pH 6.0. The divalent cations, calcium and magnesium, do not affect granular cell attachment. However, calcium in Galleria ‐anticoagulant and PBS and, to a lesser extent, magnesium in the anticoagulant, increase plasmatocyte‐glass contact. Based upon the use of selective type I protein kinase A inhibitor (Rp‐8‐Br‐cAMPS) and activator (Sp‐8‐Br‐cAMPS), active protein kinase A inhibits the adhesion of both haemocyte types. Similarly, protein kinase C inhibited by Gö 6976 enhances haemocyte adhesion whereas the enzyme activator, phorbol‐myristate‐acetate, impairs attachment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.252
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2005
Admission routes2
Has abstractyes

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