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Record W2130557504

Complications of Meckel's diverticula in adults.

2006· article· en· W2130557504 on OpenAlexaff
Jaymi Dumper, Shawn MacKenzie, Philip Mitchell, Francis Sutherland, May Lynn Quan, Daphne Mew

Bibliographic record

VenuePubMed · 2006
Typearticle
Languageen
FieldMedicine
TopicGastrointestinal disorders and treatments
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMeckel's diverticulumMedicineAnatomyUmbilicus (mollusc)PopulationHepatic diverticulumIleumYolk sacIleocecal valveDiverticulum (mollusc)BiologyInternal medicineEmbryo
DOInot available

Abstract

fetched live from OpenAlex

Meckel's diverticulum is a normal anatomic variant found in 2% of the population. It is a remnant of the vitelline duct, which is usually located on the antimesenteric border of the ileum, within about 60 cm of the terminal ileum. As a congenital variant, Meckel's diverticula are often found in children and less commonly present in the adult population. The anatomic variant was initially identified by Fabricus Hildanus in 1598; however, Johann Meckel was the first to publish a detailed description of this not uncommon finding.1 From an embryological standpoint, a Meckel's diverticulum originates when the vitelline (or omphalomesenteric) duct, which normally connects the primitive gut to the yolk sac, fails to obliterate around the seventh or eighth week of gestation. This leads to several possible anomalies, including an omphalomesenteric fistula, an enterocyst, a fibrous band connecting the intestine to the umbilicus or a Meckel's diverticulum with or without a fibrous cord connecting to the umbilicus.2–4 Anatomically, the Meckel's diverticulum is a true diverticulum containing all layers of the small intestine, arising from the anti-mesenteric border of the ileum and receiving its blood supply from a remnant of the vitelline artery, which emanates from the superior mesenteric artery. A commonly quoted “rule of 2s” also applies: (1) 2% of the population have the anomaly, (2) it is approximately 2 inches in length, (3) it is usually found within 2 feet of the ileocecal valve, (4) it is often found in children under 2 years of age and (5) it affects males twice as often as females.2–6 Although these are good general guidelines, they are not based on accurate data. In an autopsy series, 0.14%–4.5% of cadavers contained a Meckel's diverticulum.7–11 The average length of a Meckel's diverticulum is 3 cm, with 90% ranging between 1 cm and 10 cm and the longest recorded being 100 cm.11–14 The mean distance from the ileocecal valve seems to vary with age, as Yamaguchi and colleagues14 showed in their study of 600 patients, with an average distance of 34 cm for children under 2 years of age. In people aged 3–21 years, the average distance of the Meckel's diverticulum from the ileocecal valve is 46 cm and for adults is 67 cm. The Meckel's diverticulum has actually been found to occur equally in both sexes,6,15–18 but it causes complications more frequently in males.11,15,19 A good, up-to-date review of the history, embryology, anatomy, complications and treatment of Meckel's diverticulum can be found at http://www.emedicine.com/med/topic2797.htm, by Kuwajerwala and colleagues.2 Here we provide an illustrative presentation, outlining the common complications of Meckel's diverticulum in adults. We saw 2 of these cases within a 2-week period and 2 additional cases in the preceding 3 years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.030
Threshold uncertainty score0.142

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.220
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations231
Published2006
Admission routes1
Has abstractyes

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