(Carboxymethyl–Dextran)‐Modified Magnetic Nanoparticles Conjugated to Octreotide for MRI Applications
Bibliographic record
Abstract
Abstract The synthesis of (octreotide–carboxymethyl–dextran)‐modified magnetic nanoparticles (CMD‐MNPs), which were characterized by FT‐IR, AFM, TEM and XRD, and magnetic hysteresis, is described. Magnetic Resonance Imaging (MRI) experiments were performed on a 1.5 Tesla Magnetom Vision machine. The internalization of CMD‐MNPs‐OC into pancreatic cancer cells Bx‐PC3 and colon cancer cells HCT‐116 were investigated by transmission electron microscopy (TEM) and magnetic resonance imaging (MRI). The nanoparticles can be recognized specifically, via the somatostatin receptor, and which can be used as a T2 MRI contrast agent. TEM and MRI results show that somatostatin receptor can deliver OC‐modified MNPs into the cytoplasm of a cancer cell line.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".