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Regulation of TFEB and V‐ATPases by mTORC1

2011· article· en· 460 citations· W2131856428 on OpenAlex· 10.1038/emboj.2011.257

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.020
GPT teacher head0.224
Teacher spread
0.204 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The EMBO Journal
Topic
Ubiquitin and proteasome pathways
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
Massachusetts General HospitalNational Institute of Neurological Disorders and StrokeNational Institute of General Medical SciencesNational Institute of Biomedical Imaging and BioengineeringU.S. Public Health ServiceGeneralitat ValencianaYork UniversityUniversity of Texas Southwestern Medical CenterJohns Hopkins UniversityBrigham and Women's HospitalNational Cancer InstituteMarch of Dimes Foundation
Keywords
BiologyTFEBmTORC1ATPaseCell biologyLysosomeBiochemistryEnzymeSignal transductionPI3K/AKT/mTOR pathway
Has abstract in OpenAlex
no