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Record W2132696063 · doi:10.5455/bcp.20121030014051

Monoamine Oxidase Inhibitors and Neuroprotective Mechanisms

2012· article· en· W2132696063 on OpenAlexaff
Glen B. Baker, Dmitriy Matveychuk, Erin M. MacKenzie, Serdar Dursun, Darrell D. Mousseau

Bibliographic record

VenueKlinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology · 2012
Typearticle
Languageen
FieldNeuroscience
TopicNeurotransmitter Receptor Influence on Behavior
Canadian institutionsUniversity of SaskatchewanUniversity of Alberta
Fundersnot available
KeywordsNeuroprotectionMonoamine oxidasePharmacologyMonoamine neurotransmitterChemistryNeuroscienceMonoamine oxidase AMonoamine oxidase BMedicinePsychologySerotoninBiochemistryEnzymeReceptor

Abstract

fetched live from OpenAlex

There has been a resurgence of interest in recent years in monoamine oxidase inhibitors, primarily because of the demonstrated neuroprotective and/or neurorescue properties of several of these drugs in a variety of toxic situations in vivo and in vitro. The consequence has been an increased interest in possible neuroprotective effects of psychiatric drugs in general, an improved understanding of glia-neuron interactions, and the provision of important clues to development of future drugs for treating psychiatric and neurological disorders. A brief overview of some relevant studies in this area is provided in this editorial.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.240
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.062
GPT teacher head0.397
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2012
Admission routes1
Has abstractyes

Explore more

Same venueKlinik Psikofarmakoloji Bülteni-Bulletin of Clinical PsychopharmacologySame topicNeurotransmitter Receptor Influence on BehaviorFrench-language works237,207