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Record W2133358115 · doi:10.1002/pen.23108

Characterization of the viscoelastic properties of poly(ε‐caprolactone)–hydroxyapatite microcomposite and nanocomposite scaffolds

2012· article· en· W2133358115 on OpenAlexaff
Linus H. Leung, Hani E. Naguib

Bibliographic record

VenuePolymer Engineering and Science · 2012
Typearticle
Languageen
FieldEngineering
TopicBone Tissue Engineering Materials
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMaterials scienceScaffoldViscoelasticityComposite materialNanocompositeComposite numberCaprolactoneModulusPolymerCopolymerBiomedical engineering

Abstract

fetched live from OpenAlex

Abstract In bone tissue engineering, the mechanical properties of the scaffolds need to be sufficiently high to prevent material failure when bearing loads. To strengthen the scaffold, various composites have been proposed in the literature, including poly(ε‐caprolactone) with hydroxyapatite (HA). In this study, the processing of this composite using the gas foaming/salt leaching technique is examined. The control of scaffold properties by varying the processing parameters was first investigated. Then, the change in properties, with a focus on the viscoelastic properties, from the varying morphology was examined. Although an increase in scaffold density and pore size increased the scaffold modulus, it did not significantly affect the viscoelastic properties. Furthermore, the addition of HA decreased the scaffold modulus and increased the loss factor of the composite scaffolds. The more viscoelastic behavior is believed to be due to the more open structure that was created. When tested in a water bath to better simulate the physiological environment, the mechanical properties decreased by up to 85%, and the scaffolds also behaved more viscoelastically. The comparison of the scaffold properties shows the differing behavior of the scaffolds in dry and wet conditions. Hence, the environment of testing should be more carefully considered when designing experiments. POLYM. ENG. SCI., 2012. © 2012 Society of Plastics Engineers

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.059
Threshold uncertainty score0.475

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.173
Teacher spread0.167 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2012
Admission routes1
Has abstractyes

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