Evaluation effect of Hydroalcoholic Extract of <i>Eucalyptus globulus</i> and <i>Artemisia draconculus</i> compare with acyclovir against Herpes Simplex Virus Type 1
Why this work is in the frame
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Bibliographic record
Abstract
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 are two members of the herpes virus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus. The present study was carried out to determine the effect of alcoholic extract of two herbs Eucalyptus globulus and Artemisia draconculus on herpes virus compare with acyclovir in Iran during 2011. After preliminary survey, two herbs Eucalyptus globulus and Artemisia draconculus were selected as a drug for the treatment of herpes virus. HSV-1 was isolated from patients and identified by specific monoclonal antibodies. Vero cells (African green monkey kidney cells) were cultured with Dulbecco’s Modified Eagles’ Medium (DMEM) supplemented with 10% heat inactivated Fetal Bovine Serum (FBS), 100 IV/mL penicillin and l μg/mL streptomycin. Finally, the effect of these plants and Acyclovir compared with together on herpes virus. Results showed Artemisia draconculus could not reduce viral plaques significantly, however methanolic extracts of Eucalyptus globulus had a significant inhibitory effect against HSV-1 and concentration (200, 150, 50 μg/mL) has the best effect and (>200 μg/mL) Has lowest effect on HSV-1.The comparison of results exhibited that Eucalyptus globulus extract has more effects in different dilutions against HSV-1 in cell culture.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.006 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it