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Record W2133898366 · doi:10.1109/bibm.2010.5706643

Feature selection for graph kernels

2010· article· en· W2133898366 on OpenAlexaff
Mehmet Tan, Faruk Polat, Reda Alhajj

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldComputer Science
TopicComputational Drug Discovery Methods
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsCheminformaticsComputer scienceFeature selectionGraph kernelGraphPattern recognition (psychology)Artificial intelligenceFeature (linguistics)Minimum redundancy feature selectionKernel (algebra)Set (abstract data type)Data miningMachine learningKernel methodTheoretical computer scienceMathematicsSupport vector machinePolynomial kernelBioinformatics

Abstract

fetched live from OpenAlex

Graph classification is important for different scientific applications; it can be exploited in various problems related to bioinformatics and cheminformatics. Given their graphs, there is increasing need for classifying small molecules to predict their properties such as activity, toxicity or mutagenicity. Using subtrees as feature set for graph classification in kernel methods has been shown to perform well in classifying small molecules. It is also well-known that feature selection can improve the performance of classifiers. However, most of the graph kernels are not selective in choosing which subtrees to include in the set of features. Instead, they use all subtrees of a certain property as their feature set. We argue that not all the latter features are needed for effective classification. In this paper, we investigate the effect of selecting subset of the subtrees as features for graph kernels, i.e., we try to identify and keep useful features; all the remaining subtrees are eliminated. A masking procedure, which boils down to feature selection, is proposed for classifying graphs. We conducted experiments on several molecule classification datasets; the results demonstrate the applicability and effectiveness of the proposed feature selection process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.305
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2010
Admission routes1
Has abstractyes

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