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Record W2134747126 · doi:10.2217/fnl.10.46

Classifying cerebral palsy subtypes

2010· article· en· W2134747126 on OpenAlexaff
Michael Shevell

Bibliographic record

VenueFuture Neurology · 2010
Typearticle
Languageen
FieldMedicine
TopicCerebral Palsy and Movement Disorders
Canadian institutionsMontreal Children's Hospital
Fundersnot available
KeywordsCerebral palsyPhysical medicine and rehabilitationSpasticEtiologyMotor disorderGross Motor Function Classification SystemDystoniaEpilepsyMedicinePsychologyNeurosciencePathologyDisease

Abstract

fetched live from OpenAlex

Cerebral palsy is a heterogeneous syndrome that is the most common form of physical impairment encountered in pediatrics. Its heterogeneity, which is apparent in all aspects of the disorder, challenges our attempts to classify it. Several classification structures do exist that seek to further our understanding of the basic mechanisms and needs associated with this entity. The most long-standing classification approach utilizes the neurologic examination to characterize and stratify the predominant qualitative pattern of motor impairment (i.e., spastic, dyskinetic, ataxic–hypotonic or mixed), and if spastic, the particular limb distribution. The severity of cerebral palsy can be summarized in the domains of gross motor and fine motor skills by the Gross Motor Function Classification System and the Manual Ability Classification System, respectively. Frequently for patients with cerebral palsy, the major health burden may not be that of a neuromotor impairment, but rather that of the associated conditions (i.e., epilepsy, intellectual disability, etc.) affecting the individual. Finally, one may employ a mechanistic approach to stratifying according to imaging results and etiology, which are linked and provide an insight into the pathogenesis and the timing of malformation or acquired injury. While the approaches used in each of these classification schemes are separate, distinct and single axial, inter-relationships are readily apparent. Each of the classification approaches capture only one aspect of a complex disorder and is thus too simplistic. A multimodal classification approach can be employed in a complimentary fashion to provide a more holistic profile of the individual with cerebral palsy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.580
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.252
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2010
Admission routes1
Has abstractyes

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