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Record W2136107801 · doi:10.1007/s10549-008-0257-1

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

2008· article· en· W2136107801 on OpenAlexfundno aff
Sharon E. Johnatty, Fergus J. Couch, Zachary Fredericksen, Robert F. Tarrell, Amanda B. Spurdle, Jonathan Beesley, Daphne Gschwantler‐Kaulich, Christian F. Singer, Christine Rappaport, A. Fink-Retter, Susan M. Domchek, Katherine L. Nathanson, V. Shane Pankratz, Noralane M. Lindor, Andrew K. Godwin, Maria A. Caligo, John L. Hopper, Melissa C. Southey, Graham G. Giles, Christina Justenhoven, Hiltrud Brauch, Ute Hamann, Yon‐Dschun Ko, Tuomas Heikkinen, Kirsimari Aaltonen, Kristiina Aittomäki, Carl Blomqvist, Heli Nevanlinna, Per Hall, Kamila Czene, Jianjun Liu, Susan Peock, Margaret Cook, Radka Platte, D. Gareth Evans, Fiona Lalloo, Rosalind A. Eeles, Gabriella Pichert, Diana Eccles, Rosemarie Davidson, Trevor Cole, Jackie Cook, Fiona Douglas, Carol Chu, Shirley Hodgson, Joan Paterson, Frans B.L. Hogervorst, Matti A. Rookus, Caroline Seynaeve, Juul Wijnen, Maaike P.G. Vreeswijk, Marjolijn J. L. Ligtenberg, Rob B. van der Luijt, Theo A.M. van Os, Marinus J. Blok, Claudine Issacs, Manjeet K. Humphreys, Lesley McGuffog, Sue Healey, Olga M. Sinilnikova, Antonis C. Antoniou, Douglas F. Easton, Georgia Chenevix‐Trench

Bibliographic record

VenueBreast Cancer Research and Treatment · 2008
Typearticle
Languageen
FieldMedicine
TopicMetastasis and carcinoma case studies
Canadian institutionsnot available
FundersMedical Research and Materiel CommandNational Cancer InstituteMedical Research CouncilCancer Council TasmaniaNational Institutes of HealthSahlgrenska UniversitetssjukhusetFox Chase Cancer CenterLunds UniversitetUppsala UniversitetCancerfondenRadboud UniversiteitAkademiska SjukhusetHelsingin ja Uudenmaan SairaanhoitopiiriRobert Bosch StiftungVrije Universiteit AmsterdamNational Breast Cancer FoundationHuntsman Cancer InstituteBreast Cancer Research FoundationCancer Care OntarioBundesministerium für Bildung und ForschungUniversiteit LeidenNational Health and Medical Research CouncilCancer Research UK
KeywordsBreast cancerSingle-nucleotide polymorphismAlleleGATA3Estrogen receptorOncologySNPInternal medicineMedicineLinkage disequilibriumCancerGenotypeBiologyGeneticsTranscription factorGene

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.180
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.238
GPT teacher head0.410
Teacher spread0.172 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2008
Admission routes1
Has abstractno

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