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Record W2137350999

Investigation of Blood Protein Polymorphism and Estimation of Genetic Distances in Some Dog Breeds in Turkey

2004· article· en· W2137350999 on OpenAlexaboutno aff
Metin Erdoğan, Ceyhan Özbeyaz

Bibliographic record

VenueDergiPark (Istanbul University) · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic diversity and population structure
Canadian institutionsnot available
Fundersnot available
KeywordsPolymorphism (computer science)EstimationBiologyGeneticsVeterinary medicineGeographyGenotypeMedicineEngineeringGene
DOInot available

Abstract

fetched live from OpenAlex

Phylogenetic relationships in some Turkish dog breeds were investigated to determine protein polymorphisms by electrophoretic analysis. Blood samples were collected from 276 dogs including the Kangal, Akbash and German Shepherd as well as Doberman Pinscher, Setter, Pointer and Labrador breeds. Enzymes and proteins were separated electrophoretically using isoelectrofocusing gel, starch gel and polyacrylamide gel. Polymorphism on albumin (Alb), postalbumin-1 (Poa-1), postalbumin-3 (Poa-3), transferrin (Tf), and esterase (ArE) loci was detected, while no polymorphism was observed on the hemoglobin (Hb) locus. These polymorphisms were used to estimate the average heterozygosity value (h-s), F-statistics and the number of gene flow in each generation (Nm). The genetic distances (dij) were also compared among these dog breeds. Average heterozygosity values were in the range 0.32 (Doberman Pinscher) to 0.41 (Kangal Shepherd), and significant differences in heterozygosity were found among the breeds (P < 0.05). F~ISw, F~ITw and F~STw values were estimated as 0.085, 0.083 and 0.160, respectively, for whole loci in the breeds and these values were significant at P < 0.001. The estimated values of genetic distance in populations other than the Setter breed were between 0.013 and 0.242. Cluster analysis (UPGMA) results showed that the Pointer and Akbash breeds formed a cluster and then the German Shepherd joined this cluster. Finally, the Labrador breed also joined this cluster. However, the Doberman and Kangal Shepherd breeds formed a different cluster. The Setter breed did not join either and formed its own cluster. The formation of 2 distinct clusters in Kangal and Akbash Shepherd dogs reveals that these breeds have different genetic structures in terms of the investigated loci and they were not closely related to each other.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.401
Threshold uncertainty score0.440

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.181
Teacher spread0.175 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2004
Admission routes1
Has abstractyes

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