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Citrate Dialysis - Adverse Effects

2003· article· en· W2138403551 on OpenAlexvenueno aff
O J Hombrouckx Remi, Jean‐Yves De Vos

Bibliographic record

VenueHemodialysis International · 2003
Typearticle
Languageen
FieldMedicine
TopicPotassium and Related Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsTrisodium citrateMedicineDialysisHypernatremiaSodium citrateHemodialysisSodium bicarbonateBicarbonateSurgerySodiumInternal medicineMetallurgyNuclear chemistryChemistry

Abstract

fetched live from OpenAlex

Trisodium citrate 33% as anticoagulant is routinely used in several indications for acute dialysis patients, with very good clinical tolerance and results. But in chronic dialysis patients two problems arose after some weeks : 1/ In all of them hypernatremia and alcalosis developed : the pre dialysis sodium and bicarbonate level raised progressively. This could be tempered by lowering the sodium and dialysate bicarbonate concentration respectively from 140 mEq/l to 132 mEq/l and from 37 mEq/l to 25 mEq/l. 2/ The second problem was a progressive rise in serum Aluminum (Al) level in some patients: from a mean 3 μg/l to 38 μg/l; after excluding water, concentrate, dialysate, medication, etc. as possible cause, we finally controlled the Al level in the glass bottles, containing the trisodium citrate solution, and we noted very high values:35,300 μg/l. After replacement of the glass bottles by polyvinyl bags (with a neglectable Al content), the serum Al levels returned to normal. It is known that citrate chelates also the Al present in the glass of the bottles or vials themselves; our warning is not to use glass containers for citrate solutions. A short overview of different glass types is given.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.517
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.249
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2003
Admission routes1
Has abstractyes

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