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Record W2142684543

ONCOLOGISTS' PERCEPTIONS OF THE ETHICAL, LEGAL AND SOCIAL IMPLICATIONS OF GENETIC TESTING AND MICROFLUIDIC LAB-ON-CHIP TECHNOLOGY

2006· article· en· W2142684543 on OpenAlexaboutno aff
Crystal Wallin

Bibliographic record

VenueUniversity Library - University of Saskatchewan (University of Saskatchewan) · 2006
Typearticle
Languageen
FieldMedicine
TopicBiomedical Ethics and Regulation
Canadian institutionsnot available
Fundersnot available
KeywordsGenetic testingEngineering ethicsLab-on-a-chipMicrofluidic chipEthical issuesMicrofluidicsInternet privacyChipBusinessEngineeringComputer scienceNanotechnologyBiologyMaterials scienceTelecommunicationsGenetics
DOInot available

Abstract

fetched live from OpenAlex

The objectives of this study are twofold: firstly, to give an account of the current methods of knowledge production, and secondly to contribute a consultation piece on oncologists' perceptions of non-technical issues regarding the ethical, legal and social implications of microfluidic lab-on-chip technology (MF LOC).Two connected theses statements are put forth.First, understanding the transformations of knowledge production will allow for a more socially and ethically informed mode of governance to emerge.Second, it is important to consider who might use the technology and how it might impact institutions and individuals.Interviews were conducted with 31 Canadian oncologists during August 2004 to February 2005.Qualitative analysis was used to examine the oncologists' responses.It was found that of the different types of knowledge production that were reviewed (Mode-1, Mode-2, Triple Helix, and Post-normal science) the Triple Helix thesis was most supported.However, an integration of characteristics of Mode-2 with the Triple Helix thesis best accounts for the current description of knowledge production.The principles inherent in Post-Normal Science provide a starting point for developing an approach for building capacity for an independent institution that examines the ethical, legal and social concerns regarding transformative technologies.In relation to the second thesis, the results indicate that MF LOC devices have great potential to transform institutional practices and affect individual lives.And it is important to understand that the oncologists studied constructed their understanding of MF LOC technology within a scientific and biomedical repertoire consequently, future research should assess the perceptions and concerns of other groups of people that are different from the scientific and biomedical repertoire.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.430
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.007
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.202
Teacher spread0.192 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes1
Has abstractyes

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Same venueUniversity Library - University of Saskatchewan (University of Saskatchewan)Same topicBiomedical Ethics and RegulationFrench-language works237,207