Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
To detect positive Darwinian selection it is thought essential to compare two sequences. Despite its defects, "the comparative method rules." However, genes evolving rapidly under positive selection conflict more with internal forces (the genome phenotype) than genes evolving slowly under negative selection. In particular, there is conflict with stem-loop potential. The conflict between protein-encoding potential (primary information) and stem-loop potential (secondary information) permits detection of positive selection in a single sequence. The degree to which secondary information is compromised provides a measure of the speed of transmission of primary information. Thus, the sovereignty of the comparative method is challenged not only by its own defects, but also by the availability of a single-sequence method. However, while of limited utility for positive selection, the comparative method casts new light on Darwin's great question — the origin of species. Comparison of rates of synonymous and non-synonymous mutation suggests that branching into new species begins with synonymous mutations.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it