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Record W2143486402 · doi:10.1093/brain/awu361

From Nissl stains to modern concepts of brainstem function

2014· article· en· W2143486402 on OpenAlexaboutno aff
R. John Leigh

Bibliographic record

VenueBrain · 2014
Typearticle
Languageen
FieldNeuroscience
TopicVestibular and auditory disorders
Canadian institutionsnot available
Fundersnot available
KeywordsBrainstemNissl bodyNeuroscienceMedicinePsychologyPathologyStaining

Abstract

fetched live from OpenAlex

For most neurologists, the name Olszewski is associated with the 1964 seminal paper describing progressive supranuclear palsy (PSP), which was co-authored with Drs John C. Steele and J. Clifford Richardson of Toronto (Steele et al. , 1964). However, an earlier, important contribution by Dr Olszewski was his collaboration with Donald Baxter to produce their atlas, Cytoarchitecture of the Human Brainstem (1954). A third, revised and extended, edition of the atlas has now been provided by Professors Jean Buttner-Ennever and Anja Horn, of the University of Munich. Before describing what this new edition offers to neurologists and neuroscientists, a short historical summary of Olszewski, the evolution of his ideas and those of his successors concerning the brainstem—and especially the reticular formation—may help readers to understand how this atlas mirrors the development of current concepts in the clinical neurosciences. Jerzy (George) Olszewski grew up and attended medical school in what is now Vilnius, Lithuania and, during World War II, survived first Russian, and then German, invasions of his town by working ‘underground’ in a civilian army hospital (Baxter et al. , 1987). Drawing on close, long-standing ties between academics at Vilnius and the Vogt Brain Research Institute in Germany, Olszewski was able, in 1943, to obtain a position as assistant to Oskar and Cecile Vogt. The Vogts greatly influenced him and got him started on studying the brainstem reticular formation. After the war, economic circumstance forced Olszewski to move, and Oskar Vogt wrote to Wilder Penfield, who was eventually persuaded to accept him as a fellow at Montreal Neurological Institute. In collaboration with Donald Baxter (then …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.472
Threshold uncertainty score0.367

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.272
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes1
Has abstractyes

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