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Record W2143622797 · doi:10.1021/om3002558

Electronic and Steric Effects on the Lewis Acidities of Transient Silylenes and Germylenes: Equilibrium Constants for Complexation with Chalcogen and Pnictogen Donors

2012· article· en· W2143622797 on OpenAlexaff
Svetlana S. Kostina, Tishaan Singh, William J. Leigh

Bibliographic record

VenueOrganometallics · 2012
Typearticle
Languageen
FieldChemistry
TopicSynthesis and characterization of novel inorganic/organometallic compounds
Canadian institutionsMcMaster University
Fundersnot available
KeywordsChemistryChalcogenPnictogenSilyleneSteric effectsTetrahydrofuranEquilibrium constantFlash photolysisLewis acids and basesMedicinal chemistryGermaniumCrystallographyComputational chemistryStereochemistryPhysical chemistryReaction rate constantOrganic chemistryKineticsSilicon

Abstract

fetched live from OpenAlex

The Lewis acid–base complexation reactions of dimethyl-, diphenyl-, and dimesitylsilylene (SiMe 2, SiPh 2, and SiMes 2, respectively) and their germanium homologues (GeMe 2, GePh 2, and GeMes 2 ) with diethyl ether (Et 2 O), tetrahydrothiophene (THT), triethylphosphine (Et 3 P), and tricyclohexylphosphine (Cy 3 P) have been characterized in hydrocarbon solvents at 25 °C by laser flash photolysis methods. Together with previously reported (and some new) data for the complexation of the six transient tetrellylenes with methanol (MeOH), tetrahydrofuran (THF), and di- and triethylamine (Et 2 NH and Et 3 N, respectively), the results allow the first systematic assessment of the thermodynamics of Lewis acid–base complexation of simple dialkyl- and diarylsilylenes and their germanium homologues with chalcogen and pnictogen donors in solution. The equilibrium constants ( K C ) for complexation of the six species with Et 2 O span a range of ca. 10 5 M –1, decreasing in the order SiPh 2 > SiMe 2 > GePh 2 > GeMe 2 ≫ SiMes 2 > GeMes 2 . For each homologous MR 2 pair, K C is consistently 10–40 times larger for the silylene than the germylene, indicating a systematic difference in binding free energy of 1.5–2.2 kcal mol –1 . Equilibrium constants have been determined for complexation of SiMes 2 and GeMes 2 with all the donors in the series except Et 3 P, for which only a lower limit can be determined. Those for SiMes 2 decrease in the order Et 3 P > Cy 3 P > Et 2 NH > THT > Et 3 N > THF > Et 2 O; GeMes 2 is consistently less acidic, but its binding constants follow a similar ordering. The experimental data are supplemented with theoretical (Gaussian-4) calculations of thermochemical parameters for the complexation of SiMe 2 and GeMe 2 with 17 O, S, N, and P donors, which are shown to agree with experiment to within 1 kcal mol –1 for the 6 systems that have also been studied experimentally. The calculations confirm that, in general, trialkylphosphines bind most strongly, followed by amines, sulfides, and then ethers and alcohols. SiMe 2 and GeMe 2 are borderline-soft Lewis acids, stronger and softer than trimethylborane in both cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.063
Threshold uncertainty score0.747

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.208
Teacher spread0.190 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2012
Admission routes1
Has abstractyes

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