Adding psychosocial therapy to methylphenidate may not improve its effectiveness in stimulant responsive children with ADHD
Bibliographic record
Abstract
Abikoff H, Hechtman L, Klein RG, et al . Symptomatic improvement in children with ADHD treated with long-term methylphenidate and multimodal psychosocial treatment. J Am Acad Child Adolesc Psychiatry 2004;43:802–11.[OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Q Does adding psychosocial therapy to methylphenidate improve effectiveness of treatment for ADHD in stimulant responsive children? ### ![Graphic][5]</img>Design: Randomised controlled trial. ### ![Graphic][6]</img>Allocation: Not reported. ### ![Graphic][7]</img>Blinding: Phase 1 unblinded; phase 2 participants blinded to placebo substitution. ### ![Graphic][8]</img>Follow up period: 24 months. ### ![Graphic][9]</img>Setting: Two medical centres, New York and Montreal. ### ![Graphic][10]</img>Patients: 103 children aged 7–10 years with DSM-III attention deficit/hyperactivity disorder (ADHD) who had previously responded to methylphenidate; ⩾1.5 on hyperactivity index of Conners’ teacher rating scale; medication free for at least two weeks before evaluation. Main exclusions: concomitant neurological disorder; psychosis; significant medical illness; tic or Tourette’s disorder; developmental, conduct, and learning disorders; physical or sexual abuse. ### ![Graphic][11]</img>Intervention: Phase 1: methylphenidate alone (M; n = 34), methylphenidate + multimodal psychosocial treatment (M + MPT; n = 34) and methylphenidate + attention control psychosocial treatment (M + ACT; n = 35) for 1 year. All participants received individually tailored methylphenidate regimens. Phase 2: after … [1]: {openurl}?query=rft.jtitle%253DJournal%2Bof%2Bthe%2BAmerican%2BAcademy%2Bof%2BChild%2Band%2BAdolescent%2BPsychiatry%26rft.stitle%253DJ%2BAm%2BAcad%2BChild%2BAdolesc%2BPsychiatry%26rft.aulast%253DAbikoff%26rft.auinit1%253DH.%26rft.volume%253D43%26rft.issue%253D7%26rft.spage%253D802%26rft.epage%253D811%26rft.atitle%253DSymptomatic%2Bimprovement%2Bin%2Bchildren%2Bwith%2BADHD%2Btreated%2Bwith%2Blong-term%2Bmethylphenidate%2Band%2Bmultimodal%2Bpsychosocial%2Btreatment.%26rft_id%253Dinfo%253Adoi%252F10.1097%252F01.chi.0000128791.10014.ac%26rft_id%253Dinfo%253Apmid%252F15213581%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1097/01.chi.0000128791.10014.ac&link_type=DOI [3]: /lookup/external-ref?access_num=15213581&link_type=MED&atom=%2Febmental%2F8%2F1%2F9.atom [4]: /lookup/external-ref?access_num=000222246700005&link_type=ISI [5]: /embed/inline-graphic-1.gif [6]: /embed/inline-graphic-2.gif [7]: /embed/inline-graphic-3.gif [8]: /embed/inline-graphic-4.gif [9]: /embed/inline-graphic-5.gif [10]: /embed/inline-graphic-6.gif [11]: /embed/inline-graphic-7.gif
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".