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Record W2149690723

Nanotechnology in drug delivery systems

2012· article· en· W2149690723 on OpenAlexaff
Fatemeh Mirjalili, M. Soltani, Pu Chen

Bibliographic record

VenueInternational Journal of Phytomedicine · 2012
Typearticle
Languageen
FieldMaterials Science
TopicNanoparticle-Based Drug Delivery
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsNanotechnologyDrug deliveryNanomedicineMaterials scienceNanobiotechnologyNanoparticle
DOInot available

Abstract

fetched live from OpenAlex

Nanotechnology is the engineering of purposeful systems at the molecular scale. It has an impact on every industry counting semiconductors, manufacturing, and biotechnology. Biomedical nanotechnology, bionanotechnology and nanomedicine are increasing biomedicine offered hybrid fields. The oncoming generations of nanoscale biomedical/pharmaceutical products will have object specificity, carry multiple drugs, and potentially release the payloads at desired unreliable time periods. Nanotechnology is also opening up new opportunities in implantable delivery systems, which are often preferable to the use of injectable drugs, for the reason that the latter frequently show first order kinetics that may ground toxicity and decreased drug ability. Bioadhesive polymers have broadly been used in transmucosal drug delivery systems. These materials can be combined into pharmaceutical formulations, drug absorption by mucosal cells can be increased or the drug can be released at the position for an expanded duration of time. Over the past few years, nano particle ceramics have been broadly handled in a wide spectrum of biomedical requests, and drug delivery is one of the wildest developing and increasing areas for nanoceramics, drawing growing consideration. Certainly, researchers are recognizing that the amazing characteristics of nano particle ceramics exhibit excellent platforms for drug transportation and controlled release compared with polymeric platforms. This review defines various nano particle ceramics and bio/mucoadhesive polymers used in drug delivery. The presented data displays that these systems can be used excellently for continued release applications. They assure the basic demands of biocompatibility, drug loading and tolerated release sketches spreading to several weeks, and are proper materials for present implant technologies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.323

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.264
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2012
Admission routes1
Has abstractyes

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