Haemophilus influenzae type b disease control using Pentacel
Bibliographic record
Abstract
IMPACT (Immunization Monitoring Program, ACTive) investigators reported a dramatic decline in the cases of invasive Haemophilus influenzae type b (Hib) at the program's 11 (now 12) paediatric centres with the introduction of Hib conjugate vaccine programs. Between 1985 and 1995, case totals fell from 485 to 20 cases. Eight cases were seen in both 1996 and 1997. During 1997, provinces switched to Pentacel (Pasteur Mérieux Connaught Canada, North York, Ontario) as the vehicle for Hib vaccination. It is reassuring that in the two subsequent years, only a single case of Hib infection was detected among children who completed a three-dose primary series, indicating that the Hib component of Pentacel is highly effective. Of the 16 cases seen from 1998 to 1999, six had not been appropriately vaccinated because their parents refused immunization. Another child had recently emigrated from a country where Hib vaccination is not routine. The remaining cases were nonpreventable, the patient being either too young to have completed primary immunization (one case) or occurring in children vaccinated before the introduction of Pentacel (seven cases). The case total in 1999 would have been four if the vaccination not been refused in three instances.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".